سید حسین خالقی نژاد

بیوگرافی :

مدارک علمی :

1. Diploma in Natural Science, Landeh, Iran 2004.
2. B.Sc. in Biology at Kharazmi University of Tehran, Iran 2007-11. 
3. M.Sc.  in Genetics at Zabol University, Zabol, Iran and National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran. 2011-14.
4. Ph.D in Cell and Molecular Biology, at Shiraz University, Shiraz, Iran 2018-23.

افتخارات و دستاوردها :

1.    2019, Top Teacher at education in Fars province.

2.    2022, Top Researcher at Shiraz University of Technology .

زمینه‌های تدریس :

1.    Cancer Genetics 

2.    Biotechnology

3.    Genetic Engineering

4.    Cellular and Molecular Biology

5.    Genetics

Journal Papers:

1. Ghahramani, M., Shahsavani, M. B., Khaleghinejad, S. H., Niazi, A., Moosavi-Movahedi, A. A., & Yousefi, R. (2024). Efficient expression in the prokaryotic host system, purification and structural analyses of the recombinant human ACE2 catalytic subunit as a hybrid protein with the B subunit of cholera toxin (CTB-ACE2). The Protein Journal, 43(1), 24-38. https://doi.org/10.1007/s10930-023-10164-y
2. Khaleghinejad, S. H., Shahsavani, M. B., Ghahramani, M., & Yousefi, R. (2023). Investigating the role of double mutations R12C/P20R, and R12C/R69C on structure, chaperone-like activity, and amyloidogenic properties of human αB-crystallin. International Journal of Biological Macromolecules, 242, 124590. https://doi.org/10.1016/j.ijbiomac.2023.124590
3. Shahcheraghi, S. H., Shahcheraghi, S. H., Lotfi, M., Lotfi, M., Khaleghinejad, S. H., Tambuwala, Z. M., ... & Folorunso, O. (2023). Photonic nanoparticles: emerging theranostics in cancer treatment. Therapeutic Delivery, 14(4), 311-329. https://doi.org/10.4155/tde-2023-0011
4. Ayatollahi, J., Khaleghinejad, S. H., Harirzadeh, G., Lotfi, M., Hamidfar, M., Shahcheraghi, S. H., ... & Sadeghi, S. (2023). HSF1: a main aim in treatment of cancers. The Journal of Medical Research, 9(1), 1-2. https://doi.org/10.31254/jmr.2023.9101 
5. Hafizi, M., Chebotareva, N. A., Ghahramani, M., Moosavi-Movahedi, F., Khaleghinejad, S. H., Kurganov, B. I., ... & Yousefi, R. (2021). Structural and functional studies of D109A human αB-crystallin contributing to the development of cataract and cardiomyopathy diseases. PloS one, 16(11), e0260306. https://doi.org/10.1371/journal.pone.0260306
6. Khaleghinejad, S. H., Motalleb, G., Karkhane, A. A., Aminzadeh, S., & Yakhchali, B. (2016). Study the effect of F17S mutation on the chimeric Bacillus thermocatenulatus lipase. Journal of Genetic Engineering and Biotechnology, 14(1), 83-89. https://doi.org/10.1016/j.jgeb.2016.08.002
7. Shahcheraghi, S. H., Ayatollahi, J., Lotfi, M., Bafghi, A. F., & Khaleghinejad, S. H. (2016). Application of nano drugs in treatment of leishmaniasis. Glob J Infect Dis Clin Res 2 (1): 018-020. DOI: 10.17352/2455, 5363(018), 1-5.
8. Khaleghinejad, S. H., Niri, M. D., Fazilati, A., Shabani, S., & Shahcheraghi, S. H. (2016). The Role of Protein Engineering in the Design and Production of Recombinant Proteins. Int J Vaccines Vaccin, 3(3), 00067. . DOI: 10.15406/ijvv.2012.03.00067
9. pooreydy Golaki, B., Aminzadeh, S., Karkhane, A. A., Yakhchali, B., Farrokh, P., Khaleghinejad, S. H., ... & Mehrpooyan, S. (2015). Cloning, expression, purification, and characterization of lipase 3646 from thermophilic indigenous Cohnella sp. A01. Protein expression and purification, 109, 120-126. https://doi.org/10.1016/j.pep.2014.10.002
10. Khaleghinejad, S. H., Motalleb, G., Aminzadeh, S., & Yakhchali, B. (2015). Cloning, expression and characterization of chimeric BacillusThermocatenulatus Lipase in E. coli. Cellular and Molecular Research (Iranian Journal of Biology), 28(2), 202-210. 20.1001.1.23832738.1394.28.2.5.2
11. Khaleghinejad, S. H. (2020). New applications of PCR. International Conference on Human Genetics and Genomics.

Books :

1.    Biology for high school students. (Publisher:  Nano).

2.    Campbell Biology. Ed. 2020. (Publisher:  Aftab-Honar )

Research Projects :

1. The role of key genetic and post-translational modifications in structural and functional alteration of lens crystallin proteins; exploring the biochemical pathomechanisms contributing to the cataract and myopathy development, 2022. Iran National Science Foundation (INSF).

https://rtms.insf.org/ProposalCertificate.php?ID=OGRHECRJL596562Y